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PENGARUH REBUSAN DAUN SIRSAK TERHADAP KADAR GULA DARAH SEWAKTU PADA PASIEN DIABETES MELLITUSVINA ARLIN YUANITAABSTRAKDiabetes mellitus merupakan penyakit metabolik kronis yang ditandai dengan peningkatan kadar gula darah akibat gangguan sekresi insulin, kerja insulin, atau keduanya. Pengendalian kadar gula darah sangat penting untuk mencegah komplikasi. Selain terapi farmakologis, terapi nonfarmakologis seperti rebusan daun sirsak mulai banyak digunakan sebagai terapi komplementer karena dinilai mudah diperoleh, terjangkau, dan memiliki kandungan senyawa aktif yang berpotensi menurunkan kadar gula darah. Penelitian ini bertujuan untuk mengidentifikasi pengaruh rebusan daun sirsak terhadap kadar gula darah sewaktu pada pasien diabetes mellitus berdasarkan studi literatur. Penelitian ini menggunakan metode studi literatur dengan menelaah artikel ilmiah yang diperoleh dari berbagai database, yaitu Google Scholar, PubMed, Garuda, dan ScienceDirect, dengan rentang tahun publikasi 20202025. Artikel dipilih berdasarkan kriteria inklusi dan eksklusi yang telah ditetapkan, kemudian dianalisis dan disintesis sesuai tujuan penelitian. Hasil studi menunjukkan bahwa kadar gula darah sewaktu pasien diabetes mellitus sebelum diberikan rebusan daun sirsak umumnya masih tinggi, sedangkan sesudah intervensi cenderung mengalami penurunan. Sebagian besar artikel yang dianalisis juga menunjukkan adanya pengaruh signifikan rebusan daun sirsak terhadap penurunan kadar gula darah. Dengan demikian, rebusan daun sirsak dapat dipertimbangkan sebagai terapi komplementer untuk membantu pengendalian kadar gula darah pada pasien diabetes mellitus.Kata kunci: daun sirsak, diabetes mellitus, kadar gula darah sewaktu, studi literatur

THE EFFECT OF SOURSOP LEAF DECOCTION ON RANDOM BLOOD GLUCOSE LEVELS IN PATIENTS WITH DIABETES MELLITUSVINA ARLIN YUANITAABSTRACTDiabetes mellitus is a chronic metabolic disease characterized by elevated blood glucose levels due to impaired insulin secretion, insulin action, or both. Blood glucose control is essential to prevent complications. In addition to pharmacological therapy, non-pharmacological therapy such as soursop leaf decoction has increasingly been used as a complementary therapy because it is easy to obtain, affordable, and contains active compounds that may help reduce blood glucose levels. This study aimed to identify the effect of soursop leaf decoction on random blood glucose levels in patients with diabetes mellitus based on a literature review. This study used a literature review method by examining scientific articles obtained from several databases, namely Google Scholar, PubMed, Garuda, and ScienceDirect, with a publication range of 20202025. Articles were selected based on predetermined inclusion and exclusion criteria, then analyzed and synthesized according to the research objectives. The results showed that the random blood glucose levels of patients with diabetes mellitus before being given soursop leaf decoction were generally still high, while after the intervention they tended to decrease. Most of the analyzed articles also showed a significant effect of soursop leaf decoction on reducing blood glucose levels. Therefore, soursop leaf decoction can be considered a complementary therapy to help control blood glucose levels in patients with diabetes mellitus.Keywords: soursop leaves, diabetes mellitus, random blood glucose levels, literature review